Musculoskeletal Oncology
As the name suggests it deals with both benign and malignant
lesions of muscle and bone. Primary bone malignancy accounts for
just 1% of all malignancies. Other lesions are in form of metastatic
lesions and benign bone lesions which makes a large cohort of
patients
The common primary bone malignancies are:
- Osteosarcoma
- Ewings sarcoma or peripheral neuroectodermal tumours
- Chondrosarcoma
Age distribution:
- Osteosarcoma usually presents between 7-25 and after 60 years of age
- Ewings presents between 10-20 yrs of age
- Chondrosarcoma presents late in adulthood after 40 years of life.
Symptoms:
- Pain and swelling in the affected area
- Difficulty in functioning
- Pathological fractures
- Common sites for Metastasis- lungs, skeletal metastatic, abdominal organs
- Brain metastasis in case of Ewings.
The treatment involves surgery, chemotherapy and radiotherapy. The non -metastatic lesions have about 70 -80% of 5 year survival rate for osteosarcoma and Ewings sarcoma. Chondrosarcoma has about 60% 5year survival rate. But with metastatic lesion it reduces to 20-30%. The mainstay of successful treatment is early and accurate diagnosis, staging of the disease and adherence to treatment.