By Dr. Prafulla Rawate

Musculoskeletal Oncology

As the name suggests it deals with both benign and malignant lesions of muscle and bone. Primary bone malignancy accounts for just 1% of all malignancies. Other lesions are in form of metastatic lesions and benign bone lesions which makes a large cohort of patients
The common primary bone malignancies are:
  • Osteosarcoma
  • Ewings sarcoma or peripheral neuroectodermal tumours
  • Chondrosarcoma
A special note of multiple myeloma, although it arises in bone and presents with bony symptoms it is classified into haematological malignancies. Most of these are a result of mutation and no causative factor has been identified.
Age distribution:
  • Osteosarcoma usually presents between 7-25 and after 60 years of age
  • Ewings presents between 10-20 yrs of age
  • Chondrosarcoma presents late in adulthood after 40 years of life.
Symptoms:
  • Pain and swelling in the affected area
  • Difficulty in functioning
  • Pathological fractures
  • Common sites for Metastasis- lungs, skeletal metastatic, abdominal organs
  • Brain metastasis in case of Ewings.

The treatment involves surgery, chemotherapy and radiotherapy. The non -metastatic lesions have about 70 -80% of 5 year survival rate for osteosarcoma and Ewings sarcoma. Chondrosarcoma has about 60% 5year survival rate. But with metastatic lesion it reduces to 20-30%. The mainstay of successful treatment is early and accurate diagnosis, staging of the disease and adherence to treatment.

Dr. Prafulla Rawate

Associate Consultant, Orthopaedic Oncology